Ceftiofur is a semisynthetic antibiotic with activity against various gram-positive/negative anaerobic and aerobic bacteria encountered by domestic animals.

Pefloxacin is a an antibacterial agent and prevents bacterial Dna replication by inhibiting Dna gyrase (topoisomerse) .

Polymyxin B nonapeptide, a cationic cyclic peptide derived by enzymatic processing from the naturally occurring peptide polymyxin B, is able to increase the permeability of the outer membrane of Gram-negative bacteria toward hydrophobic antibiotics probably by binding to the bacterial lipopolysaccharide (LPS)